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DIM

$16.94
$16.94 - $16.94
$16.94
$16.94 - $16.94
$16.94
  • Supports natural estrogen balance
  • May help symptoms of estrogen dominance
  • Softgels, 60 servings (2-month supply)
“DIM helps me (in combination with Calcium D-Glucarate and Brocco Power) keep a handle on my post-menopausal hormones whilst I try to balance myself nutritionally.”
– KAREN B., USA – VERIFIED BUYER

How DIM can help hormones

  • Finds a natural balance of estrogen
  • Detoxifies “dirty” estrogens
  • Supports Phase I liver detoxification
  • Reduces symptoms of Estrogen Dominance
  • Supports healthier breasts (fibrocystic, painful, lumpy breasts)
  • Encourages more regular periods
  • Reduces hot flashes and night sweats
  • Eases PMS
  • Reduces symptoms of menopause

How DIM may support overall health

  • Improves sleep
  • Restores healthier weight
  • Reduces inflammatory responses
  • Reduces oxidative stress
DID YOU KNOW?
DIM is recommended over Indole-3-carbinol (I3C) as it doesn't need to be converted in the body. This creates higher efficacy and less side effects.

DIM can help women experiencing symptoms of Estrogen Dominance such as:

  • Tender, lumpy, and fibrocystic breasts
  • Hot flashes and night sweats
  • Menopause discomfort
  • Fibroids and uterine polyps
  • Endometriosis
  • PMS
  • Heavy periods
  • Irregular periods
  • Thyroid nodules
  • Cellulite and stubborn fat on the butt and thighs
  • Water retention
  • Weight gain, especially around the butt and hips
  • Infertility
  • Lack of ovulation
  • Poor sleep
  • Mood swings

3-step Natural Estrogen Balance

Estrogen needs to be cleared from the body in three steps.

Step 1: DIM frees oxidized estrogens in Phase I and the estrogens are passed on to Phase II liver detoxification.

Step 2: Toxins (including "dirty" estrogens) get passed on to the sulfation pathway where they are neutralized. Sulforaphane (Brocco Power) plays a role here.

Step 3: Toxins (including "dirty" estrogens) get passed on to the glucuronidation pathway where they are bound up by glucaric acid (Calcium D-Glucarate) and then fully eliminated from the body.

The Unusual Clogged Toilet Analogy

To graphically explain where DIM, Sulforaphane, and Calcium d-Glucarate play a role in your body, think of a clogged toilet that consists of a toilet bowl and a drain.

With DIM, you have just unclogged your toilet bowl but not the drain. DIM can open the toilet bowl but it's the sulforaphane (and Calcium d-Glucarate) that opens the drain.

What's Inside
PRODUCT EQUIVALENT IN FOOD
1 Wellena Softgel (100 mg DIM)
=
2.7 cups cooked broccoli*
Source: https://www.ncbi.nlm.nih.gov
How to use
1 Softgel
per day

Take one softgel per day, or as directed by your heath care practitioner. Can be taken after or in between meals.

Our Ingredients

Diindolylmethane

Other Ingredients: Medium Chain Triglycerides, Vitamin E, Sunflower Lecithin; Gelatin, Purified Water, Glycerine, Annatto (Softgel Ingredients)

Quality Check

A quality DIM supplement should:
  • be suspended in oil (top bio-availability)
  • contain 100 mg of di-idolyl-methane, or more
  • be free of gluten, dairy, soy, and additives
"DIM has gained the reputation of 'estrogen buster' that may resolve symptoms of Estrogen Dominance. That's an incorrect and oversimplified view of this compound. As much as it may be beneficial to some women (those who need support in clearing estrogen through Phase I liver detoxification), in reality, other compounds may be needed."

– Magdalena Wszelaki, founder of Wellena

Reviews

Frequently Asked Questions

DIM supports the beneficial metabolism of estrogen and "dirty” estrogens in Phase I liver detoxification, "freeing" toxins in the liver so that they are ready to be conjugated, or "coupled up," with specific compounds found in Phase II.
The recommended dose is 100 mg per day, which is 1 capsule per day, or as directed by your health practitioner
Take one capsule daily at any time, with or without a meal. For best results, pair with Brocco Power (sulforaphane) and Calcium D-Glucarate for complete Natural Estrogen Balance.
DIM works on Phase I liver detoxification.
The primary plant indole found in cruciferous vegetables is known as Indole 3 Carbinol (I3C), which converts to DIM in the body.I3C and DIM have been studied for their health-promoting benefits when used as supplements. While both may help support healthy estrogen metabolism, DIM may be a better option as it does not produce the unwanted side effects of I3C (including possible nausea and equilibrium issues).
Top quality DIM should use oil allowing top bio-availability and high absorption ratio. If your DIM is in a powder form, chances are that it’s not as effective. Our Wellena DIM uses MCT oil.

DIM upregulates Phase I liver detoxification which is important in estrogen clearing (and to mitigate symptoms of Estrogen Dominance) but it’s not the only liver detoxification pathway used by the body to clear “dirty” estrogens and mitigate symptoms. We also need support for Phase II liver detoxification to fully address Estrogen Dominance.

If you feel worse after taking DIM, you can support Phase II detoxification with Brocco Power (sulforaphane) and Calcium D-Glucarate for complete Natural Estrogen Balance.

Yes, It can cause orange/brownish urine. It is harmless, but be sure to drink plenty of water as it will help the detoxing along.
Yes, it will lower both the dirty and clean estrogens, so this supplement is best used for a moderate amount of time, focusing on clearing the “dirty” estrogen, and when the “dirty” estrogen is back in balance, discontinue use. For most women, this is a period of 3 to 6 months.
In the warmer months, we ship DIM with a cooler pack to prevent the softgels from sticking together in warmer weather. When the package arrives, the cooler pack may not be cool any longer. That’s ok, as it has done its job keeping things cool through the warmest parts of its journey.
Gong, Yixuan et al. “3,3′-Diindolylmethane is a novel mitochondrial H(+)-ATP synthase inhibitor that can induce p21(Cip1/Waf1) expression by induction of oxidative stress in human breast cancer cells.” Cancer research. 2006.

Omar I. Vivar, Elise F. Saunier, Dale C. Leitman, Gary L. Firestone, Leonard F. Bjeldanes, Selective Activation of Estrogen Receptor-β Target Genes by 3,3′-Diindolylmethane, Endocrinology. April 2010.

Wszelaki, M. Overcoming Estrogen Dominance. New Type Publishing. 2020. Dalessandri, Kathie M et al. “Pilot study: effect of 3,3′-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer.” Nutrition and cancer. 2004.

Zahid, Muhammad et al. “The greater reactivity of estradiol-3,4-quinone vs estradiol-2,3-quinone with DNA in the formation of depurinating adducts: implications for tumor-initiating activity.” Chemical research in toxicology. 2006.

Liu, Xiaojiao, and Kezhen Lv. “Cruciferous vegetables intake is inversely associated with risk of breast cancer: a meta-analysis.” Breast (Edinburgh, Scotland). 2013).

Gee, Jason R et al. “Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy.” European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 2016.

Xu, Yali et al. “Effect of estrogen sulfation by SULT1E1 and PAPSS on the development of estrogen-dependent cancers.” Cancer science. 2012. “Calcium-D-glucarate.” Alternative medicine review : a journal of clinical therapeutic. 2002.

How we make things to be delivered directly to you

Science. Research. Facts.

All our products are rooted in science. No BS, just clean and honest ingredients that work.

We don’t greenwash. Ever.

No greenwashing means that we don't use misleading marketing to make our products seem more green or eco-friendly. Our products really are as natural as it gets.

If it’s not squeaky clean, it’s out.

We work hard to bring you products that are safe and effective. The top offenders we never invite to the party: GMOs, hormone disruptors, gluten, soy, and dairy.

Rigorously tested

Our manufacturing facilities are GMP compliant, which means every product is carefully tested. Our products are proudly made in the US and Canada.

Time-honored traditions

Many of our products use botanicals inspired by ancient herbal traditions from around the world.

1+1 = 5

Our ingredients work synergistically, amplifying each other. We transform them into meaningful products that make a difference for your body and spirit.

Frequently Asked Questions

DIM supports the beneficial metabolism of estrogen and "dirty” estrogens in Phase I liver detoxification, "freeing" toxins in the liver so that they are ready to be conjugated, or "coupled up," with specific compounds found in Phase II.
The recommended dose is 100 mg per day, which is 1 capsule per day, or as directed by your health practitioner
Take one capsule daily at any time, with or without a meal. For best results, pair with Brocco Power (sulforaphane) and Calcium D-Glucarate for complete Natural Estrogen Balance.
DIM works on Phase I liver detoxification.
The primary plant indole found in cruciferous vegetables is known as Indole 3 Carbinol (I3C), which converts to DIM in the body.I3C and DIM have been studied for their health-promoting benefits when used as supplements. While both may help support healthy estrogen metabolism, DIM may be a better option as it does not produce the unwanted side effects of I3C (including possible nausea and equilibrium issues).
Top quality DIM should use oil allowing top bio-availability and high absorption ratio. If your DIM is in a powder form, chances are that it’s not as effective. Our Wellena DIM uses MCT oil.

DIM upregulates Phase I liver detoxification which is important in estrogen clearing (and to mitigate symptoms of Estrogen Dominance) but it’s not the only liver detoxification pathway used by the body to clear “dirty” estrogens and mitigate symptoms. We also need support for Phase II liver detoxification to fully address Estrogen Dominance.

If you feel worse after taking DIM, you can support Phase II detoxification with Brocco Power (sulforaphane) and Calcium D-Glucarate for complete Natural Estrogen Balance.

Yes, It can cause orange/brownish urine. It is harmless, but be sure to drink plenty of water as it will help the detoxing along.
Yes, it will lower both the dirty and clean estrogens, so this supplement is best used for a moderate amount of time, focusing on clearing the “dirty” estrogen, and when the “dirty” estrogen is back in balance, discontinue use. For most women, this is a period of 3 to 6 months.
In the warmer months, we ship DIM with a cooler pack to prevent the softgels from sticking together in warmer weather. When the package arrives, the cooler pack may not be cool any longer. That’s ok, as it has done its job keeping things cool through the warmest parts of its journey.